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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFF
All Species:
14.85
Human Site:
S186
Identified Species:
32.67
UniProt:
Q9GZY8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZY8
NP_064579.3
342
38465
S186
S
A
P
R
N
K
I
S
R
F
Q
A
P
I
S
Chimpanzee
Pan troglodytes
XP_516131
372
41638
S216
S
A
P
R
N
K
I
S
R
F
Q
A
P
I
S
Rhesus Macaque
Macaca mulatta
XP_001110642
341
38439
S185
S
A
P
R
N
K
I
S
R
F
Q
A
P
I
S
Dog
Lupus familis
XP_850079
342
38482
S186
S
A
P
R
N
K
I
S
R
F
Q
A
S
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCP5
291
32913
P160
P
Q
A
R
V
C
P
P
H
M
L
P
E
D
G
Rat
Rattus norvegicus
Q4KM98
218
24952
L87
T
P
F
K
P
L
A
L
K
T
P
P
R
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519323
251
27935
T120
K
T
P
P
R
V
L
T
L
S
E
R
P
L
D
Chicken
Gallus gallus
XP_001233530
330
37495
P173
T
V
P
R
N
K
M
P
R
F
Q
S
P
L
S
Frog
Xenopus laevis
Q6DD53
219
24655
K88
N
I
G
T
L
A
L
K
T
P
P
R
V
L
T
Zebra Danio
Brachydanio rerio
Q503U3
275
31342
K144
R
R
N
G
Q
I
N
K
H
D
F
A
S
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198768
213
23716
A81
Q
H
V
G
A
R
Q
A
P
R
N
L
D
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
97.6
95
N.A.
80.1
60.5
N.A.
63.1
81.5
42.4
45.3
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
100
90.3
98.2
97
N.A.
82.4
62.8
N.A.
67.5
88.8
50.2
61.4
N.A.
N.A.
N.A.
N.A.
34.8
P-Site Identity:
100
100
100
86.6
N.A.
6.6
0
N.A.
13.3
60
0
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
6.6
26.6
N.A.
40
86.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
10
0
10
10
10
10
0
0
0
46
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
19
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
46
10
0
0
10
0
% F
% Gly:
0
0
10
19
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
19
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
10
37
0
0
0
0
0
0
28
0
% I
% Lys:
10
0
0
10
0
46
0
19
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
10
19
10
10
0
10
10
0
37
10
% L
% Met:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
10
0
46
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
10
10
55
10
10
0
10
19
10
10
19
19
46
10
0
% P
% Gln:
10
10
0
0
10
0
10
0
0
0
46
0
0
0
0
% Q
% Arg:
10
10
0
55
10
10
0
0
46
10
0
19
10
0
0
% R
% Ser:
37
0
0
0
0
0
0
37
0
10
0
10
19
0
55
% S
% Thr:
19
10
0
10
0
0
0
10
10
10
0
0
0
0
10
% T
% Val:
0
10
10
0
10
10
0
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _